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Medical Abortion

Medical abortion involves taking pills (2 different medicines) to end the pregnancy. The effects of abortion pills result in a process similar to a miscarriage. Abortion pills (mifepristone and misoprostol) are a safe and effective way to end a pregnancy in the first 12 weeks of pregnancy. The term “medication abortion” refers to the use of either the combination of mifepristone plus misoprostol or misoprostol taken alone to end a pregnancy. Medication abortion works better, is quicker and has less risk of complications when done earlier in pregnancy, so women who decide to have an abortion should do so as early as possible.

Medication abortion usually involves taking a combination of the two medicines mifepristone and misoprostol. If mifepristone is not available, misoprostol can also be used alone. In the absence of mifepristone, a woman will need to take more misoprostol pills, the process tends to be longer, and she may experience more side effects to achieve comparable success.

Depending on the setting and context, a woman can have a medication abortion in a health facility, at home (or another private place where she feels secure and comfortable), or in a combination of the two. Women can have a successful abortion if they have accurate information, access to quality medications, and know the signs of complications for which they should seek immediate medical care. Medication abortion is suitable for women of all ages and sizes, including adolescents. An uncomplicated medication abortion will not affect a woman’s ability to carry future pregnancies.

A visit to a health facility is not usually necessary following an uncomplicated medication abortion. If a woman is unsure that the abortion was successful, she may choose to visit a health facility to confirm that she is no longer pregnant.

What are mifepristone and misoprostol

Mifepristone is a medicine that blocks the hormone needed for a pregnancy to progress. Misoprostol is a medicine that causes the uterus to contract and expel a pregnancy.

Both mifepristone and misoprostol are available as tablets. In many countries, misoprostol alone is sold under the brand name Cytotec. Misoprostol is sometimes sold as a stomach ulcer medication and/or for other indications like the treatment of heavy bleeding after childbirth.

Mifepristone and misoprostol are sometimes available together in a combination pack (sometimes known as a “combipack”). Combipack and mifepristone brand names vary by country, so you should know which names these drugs are sold under in your setting.

Misoprostol comes in various dosages. It is most sold in a pack of several 200 microgram (mcg) pills. The 200mcg pill is the best option for medication abortion, and multiple pills are needed for each abortion. They should only be taken according to the dosages recommended.

Misoprostol breaks down when exposed to humidity, compromising its ability to act on the body the way it should. To help ensure a high-quality product, misoprostol should only be bought and used when it is packaged in double-sided aluminum pill casing. The aluminum pill case should be kept sealed until the time of administration.

Medication abortion using mifepristone and misoprostol

Using mifepristone in combination with misoprostol is a highly effective (approximately 95% effective) and safe way to end an early pregnancy.

Most women generally experience an abortion within the first 24 hours after taking the dose of misoprostol, although it sometimes takes longer. The pregnancy is generally expelled quicker when a woman takes mifepristone in combination with misoprostol compared to using misoprostol alone.

How to take mifepristone with misoprostol in first 12 weeks since last period

  • Swallow the first pill (mifepristone) with water.
  • Wait 1–2 days
  • Take Misoprostol either:
    • Place 4 tablets under the tongue, hold them there for 30 mins, then shallow whatever is left.
    • Place 2 pills (misoprostol) between the cheek and lower gum on each side of her mouth (4 pills total) and keep them there until they dissolve. After 30 minutes, she should swallow whatever is left with water

Medication abortion using misoprostol alone

If mifepristone is not available, misoprostol can also be used alone to end a pregnancy.

Taking misoprostol alone is still an effective way to end a pregnancy, but it is more effective when taken in combination with mifepristone.

Most women will experience an abortion within the first 24 hours after taking misoprostol, although it sometimes takes longer.

When misoprostol is used alone, a woman will need repeat doses of the medicine to achieve a successful abortion.

The recommended regimen is three repeat doses of 800mcg misoprostol placed either under the tongue (sublingual route) or against the cheek (buccal route) every three hours. Since more doses are required, women should make sure they have at least 12 pills of 200mcg available to take.

Even if bleeding starts after the first or second dose, the woman should take all three doses for best results. Sometimes, to achieve a successful abortion, more than three doses of misoprostol (800mcg) may be needed.

Inserting misoprostol pills into the vagina (vaginal route) works well too but is not recommended in legally restricted settings as the pills may be detectable even several hours later. In some cases, women seeking medical attention have been reported to the police for having an abortion without the approval of a health provider.

How to take misoprostol alone in first 12 weeks since last period

  • Place the 4 pills (misoprostol) under the tongue and hold them there until they dissolve. After 30 minutes, swallow whatever is left with water. take more pills the same way every 3 hours, taking 12 pills total.
  • Place 2 pills (misoprostol) between the cheek and lower gum on each side of the mouth (4 pills total) and keep them there until they dissolve. After 30 minutes, swallow whatever is left with water. take more pills the same way every 3 hours, taking 12 pills total

Which contraceptive methods can be used with or after medication abortion?

With the exception of the intrauterine device (IUD), most methods of contraception can be started right away with medication abortion (as early as the day of taking the first abortion pill—mifepristone or misoprostol). Choices include:

Contraceptive implants

Trained providers can perform a minor procedure to place and remove a small plastic rod that is kept under the skin on the inside of a woman’s arm. Depending on the type used, the implant can remain in place and prevent pregnancy for 3-5 years. An implant can be inserted as early as on the day you take the first abortion pill (mifepristone or misoprostol).

Intrauterine device (IUD)

A small, T-shaped device inserted into a woman’s uterus by a trained health provider. Depending on the type used, the IUD can stay in place and prevent pregnancy for up to 12 years. A health provider can remove the device at any time. An IUD should be placed only when it is reasonably certain a woman is no longer pregnant after taking abortion pills.

Contraceptive injection

A trained provider injects the contraceptive into a muscle in the arm or leg once every 1-3 months, depending on the type used. In some settings, women can self-administer injectable contraceptives if they have the right training and access to a health provider when needed. A contraceptive injection can be given as early as the day when the woman takes the first abortion pill (mifepristone or misoprostol). In some settings, this injectable contraception may be available at the same pharmacy or drug seller where a woman buys her abortion medications.

Oral contraceptive pills

There are two types of oral contraceptive pills: the “combined” oral pill (which contains two hormones) and the progesterone-only pill. A woman must swallow either type of pill and must take them regularly and consistently to prevent pregnancy. The contraceptive pill can also be started as early as the first day of medication abortion and may be available to buy at the same place women buy abortion pills.

condoms content

Condoms (male and female)

Consistent and correct use of a condom is good for preventing the sexual transmission of HIV and reducing the risk of other sexually transmitted infections, such as chlamydia, gonorrhea, and syphilis. They are also effective in preventing pregnancy if used every time and correctly.

Tubal ligation

Tubal ligation, also known as female sterilization, is minor surgery to permanently prevent pregnancy. This a permanent method of contraception and can only be provided by a trained clinical provider.